Previous verses mentioned the treachery and ill-will of the hypocrites. The present verses comfort the Holy Prophet ﷺ asking him not to grieve over the mischief made by the disbelievers for they cannot harm him in any way.
The last verse Ali 'Imran 3:178 ⧉ carries a refutation of the false notion about disbelievers: How can they, while obviously prospering in the present world, be regarded as victims of Allah's wrath and rejection?